Tuesday, January 21, 2014

Blog 22 - two parts: Belief and Pain

I’m not religious. I used to be. I was an altar-boy when I was 9. I went to priest training college for 3 years from the age of 11. But then I begin to think. And the belief in someone/something unseen that is interested in me doesn’t make sense.

It is a cause of great disquiet when people tell me that my cancer was God’s will. The belief that God could wish me ill would drive me insane.

I have no problem with people praying to their God for my well-being: Knowing that people are concerned about me adds to my strength of will. When I wish people well, I send positive thoughts; it is my equivalence to prayer. I believe that the energy output by our bodies is available for use by other living things. If you spend time with happy people, you become happy. If you spend time with bad people, you become bad. You can use positive thoughts to create positive environments. Prayers work in this way.

I have no problem with people rationalising their anxieties for my predicament through ‘blaming’ it on something else – even blaming it on my ‘sins’. But personally, I refuse to blame anything for my cancer. It happened. It is a natural occurrence.
The dichotomy of life is that cells both try to reproduce precisely and strive to change their existence – in case there is an advantage – although evidence points to the fact that most changes fail. When a cell divides in a different way than that type of cell usually does it can have one of three outcomes: It can make no difference – the cell continues to perform in the same way, it can fail (and so the cell dies) or it can work (the cell survives). In this last case there can also be three outcomes: It can make no difference (there is no change to the overall organism’s performance), it can work (the organism becomes better), or it can fail (the organism becomes weaker). The things we eat, drink, inhale, inject or otherwise absorb or ingest can change the make-up of cells. Another thing that causes change is radiation. Random radiation from the solar system is bombarding the earth at all times, man-made radiation is also penetrating people: Each ‘bit’ of radiation can cause any cell that it hits to change: That cell might die there and then; it might cease to divide; it might live and mutate.
Some of these changes in cell characteristics are good – they improve, say, eyesight or memory, they increase height or strength; some are so bad that they can be described as malignant – they cause damage; some can be described as cancerous – they both cause damage and prevent repair – Clever? Blessed? Sinful? Evil? No, nature. The changes mentioned here are not intentional – neither by me, by anyone hexing or blessing me, nor by any other outside agency having a concern for my welfare. As I said earlier, I do believe that positive thoughts can influence welfare - how, well I can't tell you - I suppose I better try to find out.

And the way I dealt with cancer? It was my choice. It was my determination. Bolstered by your prayers and best wishes and belief in me. This hasn’t been a test of me. This has happened to me, that’s all.
My recovery has been successful due to our positivity and the knowledge, experience and determination of the medical teams who looked after me – and crucially who managed the after effects of their treatment through pain control. 

Which leads me neatly into the second part of this blog:

Pain.

The 4 types of pain.
  •         When cells are damaged, they produce large quantities of an enzyme called Cyclo-oxygenase-2. This enzyme, in turn, produces chemicals called prostaglandins, which send pain signals to the brain. They also cause the area that has been damaged to release fluid from the blood to create a cushion so the damaged cells don't become more damaged.
  •        Pain also comes from physical pressure and from sensory stress. Probably both the same pain caused by reduced blood flow to muscles in the affected area.
  •        Neuropathic pain:  E.g. neuralgia, is caused by dysfunction of the nerve cells. (This pain can also occur in cancer patients and more so following chemotherapy).
  •        In women, menstrual pain is caused by the body deliberately releasing pain causing chemicals in order to cause muscular contraction of the uterus.

6 classes of pain treatment (apart from removing the source of the problem!)
  • Opioids partially block pain messages getting to the brain, but also change the way the brain perceives pain. And also increases tolerance to pain.

Opioids are usually divided up into two groups:
·        Weak opioids - these include codeinedihydrocodeine, and tramadol.
·        Strong opioids – these include buprenorphine, methadone, diamorphine, fentanyl, hydromorphone, morphine, oxycodone, and pethidine.

  •        Salycilic Acids (natural and synthetic versions) affect the source of the pain by binding to the cylo-oxygenase-2 enzymes and stopping them from producing prostaglandins. Prostoglandins in the bloodstream can cause clotting, so Salycilic acid can reduce this. The acid also reduces the production of thromboxane, a chemical that makes blood platelets sticky which can block an artery.

There are over 20 types. They include: aceclofenac, acemetacin, aspirin, celecoxib, dexibuprofen, dexketoprofen, diclofenac, etodolac, etoricoxib, fenbufen, fenoprofen, flurbiprofen, ibuprofen, indometacin, ketoprofen, mefenamic acid, meloxicam, nabumetone, naproxen, piroxicam, sulindac, tenoxicam, and tiaprofenic acid
(Aspirin and ibuprofen can also reduce temperature).

  •        Paracetemol: affects the volume of pain and lowers a high body temperature. Prostoglandins are also produced in the brain to enhance the perception of pain – paracetemol reduces this production in the brain but not at the source of the pain and does not reduce inflammation.

  •        Anti-depressants and anti-epileptics: For neuropathic pain.
  •        TENS machine (transcutaneous electrical nerve stimulation).
  •        Psychotherapy. Change perception of pain or reduce some sensory stress.


NOTES:
In medications, drugs can be single or combined. Usually an opioid with one of the others.

Aspirin: (From willow bark. First used in 1899. Salicin also occurs in myrtle and birch) Reduces fever and inflammation and blocks messages to the brain.

Morphine: (Opiate, from opium poppies.) Mimics bodies pain defences (see Endorphins). Relieves pain, relaxes muscles and causes drowsiness. Addictive.

Endorphins: (Discovered in 1970s at Aberdeen University). The body’s own painkiller defence mechanism.  Exist/released in the brain. Especially during exercise and acupuncture.

 The information on pain is my interpretation of literature: Do NOT rely on it: Seek the advice of experts if you are in pain.

Regards
Frank

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